WHAT IS KPV (LYSINE - PROLINE - VALINE )
KPV (Lysine-Proline-Valine) is a tripeptide that is naturally produced in the body. It is a C-terminal peptide fragment of the hormone alpha-MSH. KPV has shown promise in treating a number of diseases, including inflammatory bowel disease (IBD)
KPV is known as a potent anti-inflammatory peptide showing great promise in various disease conditions. Particularly noteworthy is its active research in the treatment of inflammatory bowel disease, where it has demonstrated substantial potential.
Animal studies have consistently indicated that KPV is both safe and effective when administered through various routes, including oral, intravenous, subcutaneous, and transdermal methods. In addition, research in wound healing has shown the potential benefits of KPV and other alpha-MSH derivatives, such as accelerated wound healing, reduced infection rates, anti-inflammatory effects, and improved cosmetic outcomes. KPV could potentially become essential not only in wound healing but also in scar reduction post-surgery.
WHAT ARE THE BENEFITS OF KPV
The most significant benefit from KPV research is its remarkable ability to alleviate and reduce intestinal inflammation. In mouse models of inflammatory bowel disease (IBD), KPV showed significant positive outcomes by diminishing inflammatory infiltrates. In the study, mice treated with KPV demonstrated accelerated recovery and exhibited a larger weight gain compared to those receiving a placebo.
KPV has several benefits, including:
- Healing wounds and injuries
- Strengthening the immune system
- Improving skin health
HOW DOES KPV WORK
KPV works by increasing wound healing, acting as an anti-microbial and reduces inflammation.
Working as an anti-inflammatory, KPV exerts its anti-inflammatory function inside cells, where it inactivates inflammatory pathways. It works directly with inflammatory signalling molecules inside the cell where it enters the nucleus of the cell and, once there, can inhibit the interaction of inflammatory substances and molecules.
In addition to its anti‐inflammatory effect, KPV also has antimicrobial effects against several pathogens with two in particular S. aureus and C. albicans.
In one study, KPV significantly inhibited S. aureus from forming colonies
Research in wound healing shows KPV can speed up the process of wound healing, reduce infection, fight inflammation, and lead to better cosmetic results.
Often while the wound is healing, wounds, various microbes can enter and delay the process. KPV, with its anti-inflammatory and anti-microbial properties, has shown to aid by combatting these microbes and healing wounds.
WHAT IS THE DOSAGE OF KPV
KPV is supplied in capsule form. Common strengths include:
- 250 mcg capsules
- 500 mcg capsules
Dosing recommendations are typically one capsule daily. Sart with lowest dose first.
WHAT ARE THE SIDE EFFECTS OF KPV
KPV has minimal side effects and exhibits excellent oral subcutaneous bioavailability.
KPV is a naturally derived peptide without any notable side effects. There is always the chance of potential interactions with other medications a person may be taking. Therefore it is important to work with an experienced practitioner when taking KPV or any other peptides.
CAN I COMBINE KPV WITH LL-37
Yes. You can combine both.