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WHAT IS DIHEXA
Dihexa (also known as PNB-0408 or N-hexanoic-Tyr-Ile-(6) aminohexanoic amide) is a six-amino-acid peptide directly derived from Angiotensin IV (Ang IV). It is considered a nootropic drug that affects the central nervous system and assists in the regulation of insulin and memory / recall.
Ang IV is, similar to a potent vasoconstrictor known as angiotensin II. It has been shown to increase recall in animal models of learning and memory.
Discovered in 2007 and first released in 2012, Dihexa continues to show improvement in cognitive function and the reversal of neurological damage.
WHAT ARE THE BENEFITS OF DIHEXA
- Reduce the neurological damage induced by Alzheimer's Disease
- Enhance cognition in seniors with cognitive difficulties
- Show benefit in treating Parkinson's disease
- Improved problem solving skills
- Enhanced creativity
HOW DOES DIHEXA WORK
The exact mechanism is unknown, but many researchers believe DIHEXA creates new synapses. It is designed to cross the blood-brain barrier to not only increase memory but also retrieval of information.
It is thought that is can also help improve motor dysfunction by creating new synapses.
In disease such as Alzheimer's disease, many drugs target the reduction of a chemical in the brain that contributes to the disease where as DIHEXA creates more channels of communication to in essence reverse the disease process.
The same is true of Parkinson's disease where studies have shown promise to increase hepatocyte growth activator to prevent the movements in the disease.
WHAT IS THE DOSAGE OF DIHEXA
DIHEXA is supplied in capsules and a topical gel. Capsule strengths are 2 mg, 10 mg, 20 mg , 25 mg.
DIHEXA gel strength 20 mg/gm typically in a 30 gm volume.
- Oral is 1 capsule daily Exact dosing varies depending on the person and use
- Topical is 1-2 clicks daily to the inner part of the forearm
WHAT ARE THE SIDE EFFECTS OF DIHEXA
The side effects are not well documented. Patients have reported:
- reduced attention span
- mood swings
- change of taste
- increased anxiety